Behcet's disease is systemic vasculitis of unknown etiology, characterized by recurrent erosive and ulcerative lesions of the mucous membrane of the mouth and genital organs, frequent involvement of the eyes, joints, organs of the gastrointestinal tract (GI tract), central nervous system. The variety of clinical manifestations and the uncertainty of the origin of this syndrome lead to diagnostic errors and inadequate therapy.
The etiology and pathogenesis of Behçet's disease remain unclear, but there is some evidence of the involvement of genetic, immunological and infectious factors in the onset of the disease. Behcet's disease in the Republic of Uzbekistan in recent years has been detected more often, but these figures on incidence do not reflect the real picture, since underestimation of this pathology is associated with low awareness of doctors of related specialties, resulting in patients receiving non-specialized treatment in other medical institutions, which is cause of complications.
Diagnosis of Behcet's disease is established on the basis of criteria developed by the International Study Group for this disease. In this thesis, we present our materials and methods for studying clinical manifestations in 17 patients with Behcet's disease, among people of Uzbek nationality who were on inpatient treatment at the Republican Specialized Scientific and Practical Medical Center for Dermatovenerology and Cosmetology of the Ministry of Health of the Republic of Uzbekistan in 2017-2018.
The foregoing dictates the need for a more detailed study of the results: immunological, genetic, microbiological, PCR studies and it is planned to develop diagnostic and therapeutic techniques.To properly establish a diagnosis and reliable registration of BD it is necessary to conduct seminars among dermatovenerologists and doctors of related specialties.