HYBRID EVENT: You can participate in person at Paris, France or Virtually from your home or work.
Makoto Senoo, Speaker at Dermatology Conferences
Cell Exosome Therapeutics Inc, Japan
Title : Transcription Factor p63 and Stem Cell Diseases


Homeostasis and regeneration of the skin are maintained by self-renewal, proliferation, and differentiation of tissue-specific stem cells. We have shown previously that the transcription factor p63 plays an essential intrinsic role in regulating self-renewal of skin stem cells. In this keynote speech, I will present three short stories developing in our laboratory surrounding the control of homeostasis and regeneration of the skin.

  1. Control of the cell cycle progression in skin stem cells by p63.
  2. Regulation of dermal adipocytes by skin stem cells via paracrine signaling.
  3. Rapid enrichment and expansion of skin stem cells for regenerative medicine.


Dr. Makoto Senoo started his research career as a post-doctoral research fellow at Harvard Medical School in 2002. He then opened his own research laboratory at the University of Pennsylvania School of Veterinary Medicine. Subsequently, he moved to the Boston University School of Dental Medicine and continued working on the p63 biology since its discovery in 1998. After 20 years of stay in the US, Dr. Senoo returned to Japan in late 2022, where he focuses on the development and manufacturing of stem cell- and exosome-mediated therapeutic strategies.