Kimihiko Okazaki

Title : A handy and extremely reliable method for improvement of allergic physical constitutions

Abstract:

Title: A Handy and Extremely Reliable Method for Improvement of Allergic Physical Constitutions
Author: Kimihiko Okazaki
Address: Okazaki Medical Clinic, Ukyo-ku, Kyoto, Japan
Text: It is well established that the cause of allergic physical constitution is allergen-specific antibodies that are combined to the mast cells. Acording to the traditional concept, replacements of allergen-specific antibodies with non-specific antibodies are impossible. On the other hand, it is also well established that an equilibrium state exists among antibody molecules in the vicinity of mast cell surfaces. Obviously, these two concepts are mutually contradictory. In my opinion, the traditional concept is incorrect. Evidence therefor is the success in improvement of physical allergic constitution by a number of intra-dermal injections with non-specific antigen preparations, for example, Tuberculin, Influenza vaccine, Measles vaccine, etc. Practically, these non-specific antigen preparations are diluted 1000-fold with 100 ml of saline solutions. Practically, again, each 0.1ml of them is mixed with 100ml of saline. One-tenth ml of the diluted non-specific antigen solution was injected intra-dermally at upper arm. Success rate has been virtually 100%.
References:
(1) Turton, J.A. (1976): IgE, parasites, and allergy, Lancet, Vol.2, p.686.
(2) Okazaki, K. (2007): Treatment of Allergic Diseases: Application to Clinical Practice of a New Concept of Mutual Substitutions of Antibody Molecules on the Surface of Mast Cells, Allergy, Asthma, and Clinical Immunology, Vol.3, p.36.

Biography:

Born in Osaka in March, 1933. Graduated from Kyoto University Faculty of Medicine in  March, 1959.  Engaged in Biochemical Research at Department of Hygiene,Kyoto University Faculty of Medicine, Depatment of Medical Chemistry, Kyoto University Faculty of Medicin, Departments of Physiology, Microbiology, Anatomy and Cell Biology, and Pathology, University of Pittsburgh, School of Medicine, and Department of Biochemistry, University of Ottawa during April, 1960~July, 1981.  Worked as an internist at several hospitals as follows: Kansai Medical College Hospita at Kohri, Otowa Hospital, Takeda Hospital, Shirakawa Central Hospital at Saitama Prefecture, Kisen Hospital at Katsusika, Tokyo, Ichijokai Hospital at Ichikawa, Chiba, Itabashi Hospital at Itabashi, Tokyo.  Opened my own clinic at Ukyoku, Kyoto on September 15, 1989.