A foray into the world of PRP mechanisms in dermatology and its outcomes

Title : A foray into the world of PRP mechanisms in dermatology and its outcomes

Abstract:

Platelet-rich plasma (PRP) therapy has gained traction in the scientific field due to its potential regenerative effects and great benefit–risk profile. This lecture extensively explores the most studied PRP mechanisms according to the etiopathogenesis of skin diseases: cellular proliferation, matrix formation, regulation of inflammation, angiogenesis, and collagen synthesis. The presentation will focus on PRP’s benefits and clinical relevance in wound healing, alopecia, pigmentary disorders, scars, rejuvenation, lichen sclerosus, and other inflammatory dermatoses. This update will deepen the dermatologist's confidence in the use of PRP in the treatment of skin diseases as well as for beauty purposes (rejuvenation). The lecture will encompass a variety of clinical cases.

Audience Take Away Notes:

• The audience will broaden their knowledge of the PRP method and will be able to apply it in their daily practice. They would become more familiar with the power of PRP that has changed the lives of many patients (e.g. lichen sclerosus in females and males), without any significant adverse events. Introducing this modern technique, with promising results and high availability, represents a major contribution to their daily workload. Among other PRP benefits, I would emphasize: non-surgical lifting, enhancing the before and after of hair transplantation results, and a stellar complementary therapy to botulinum toxin and fillers use
• This presentation will also highlight technical details such as the manual injection technique and choosing the most suitable PRP kit based on one's needs. Recently, one of the papers we published (December 19th, 2023) on the subject was selected as the cover of the January 2024 issue of the Biomedicines Journal. Currently, I am conducting a Ph.D. thesis on the topic of PRP use in dermatology. Hence, PRP and thrombocyte molecular mechanisms of action in skin disorders represent a hot topic of 2024

Biography:

Prof. Olga Simionescu, M.D., has been the clinical head of the Dermatology I Department, Colentina Clinical Hospital, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania over the last 15 years. She is an expert in dermoscopy and skin surgery, with a special interest in mucosal lesions, and has published important papers in high-ranked international journals. As a Professor of Clinical Dermatology, she is highly qualified in general Dermatology and Venereology, with a special interest in skin cancers, connective tissue disorders, inflammatory skin diseases, lasers, skin surgery, regenerative and cutaneous molecular medicine (keratinocytes, melanocytes, telocytes).