Title : A new regenerative medicine concept for face and neck rejuvenation: Combined use of stem cells and two laser technologies for fractional phototermolysis and rapidly healing the injured tissue
Abstract:
Background: stem cells represent a powerful new tool in regenerative medicine since they can promote regeneration of aged tissues by replacing apoptotic and necrotic cells with healthy ones and show antiapoptotic and antinfiammatory properties; many reports have well demonstrated clinical and histologic evidence of the potential benefit of fractional phototermolysis in the treatment of photo damaged skin.
Objective: This report evaluated the efficacy of combination of stem cells and two laser technologies for face and neck rejuvenation: The wavelength 1450 nm for micro coagulation and the wavelength 980 for stimulation the production of neo-collagen and elastin.
Methods: 450 patients with mild to high cutaneous photodamage received 4 successive laser treatments and stem cells applications at 3 weeks intervals. Clinical improvement of treatment areas was determined by comparative analysis of photographs at baseline and 1, 6, 12, 24 months post treatment. At each time a specific skin software allows to evaluate wrinkles density, skin dark and light, spot density etc.
Results: A greater than 85% clinical improvement in photo damage at the 24 month follow up was achieved in nearly 95% of patients. All patient reported improvement of the texture of the skin and visible reduction of wrinkles with no side effects with a very high patient satisfaction rate.
Conclusion: These first clinical results seem to show that combined use of this laser technology and stem cells offers a new effective and safe modality for face and neck rejuvenation.
