Successful treatment of combination of eosinophilic granuloma of the face and prurigo on trunk

Title : Successful treatment of combination of eosinophilic granuloma of the face and prurigo on trunk

Abstract:

Introduction & Objectives: Unusual combination of prurigo on trunk and arms and eosinophilic granuloma on the face was revealed in a patient 73 years old. Long history of differential diagnosis and search for the adequate treatment for many years was ended in results of the biopsy and long list of medications including topical and systemic glucocorticosteroids, antiviral treatment, as well as Dapsone that allow long remission.  
Materials & Methods: Patient 73 years old applied with complains on rash on the skin of the face and trunk with itch. She was ill during 7 years when first noted rash on her back than later – face. According to the histological examination of the biopsy of the face, eosinophilic granuloma of the face was diagnosed. The treatment by systemic and topical glucocorticosteroids, tacrolimus, valtrex gave a temporary effect, the use of dapsone 100 mg during 6 months gave a long remission. Concomitant diseases: nodular goiter, ischemic heart disease, hypertension, torticollis. Occupational hazards: she worked as a painter, had allergic reactions to varnishes and paints
Results: During the treatment the patient noticed improvement on the skin of face and trunk – reduction of the lesions and itch
Conclusion: Long use of Dapsone under control of blood examination gave a good result to make the long existing eosinophilic granuloma more stable and avoid exacerbation.

Audience Take Away Notes:

The presentation will give the information about diagnistics and treatment if prurigo with resistant to traditional therapy form. The doctors will better differentiate the skin disease and find the adequate treatment. The case illustrates an unique experience of successful treatment of prurigo by dapson.

Biography:

Bobko Svetlana MD, PhD senior research fellow of Moscow scientific and practical center of dermatovenereology and cosmetology graduated with honours from Moscow Medical Academy named after I.M. Sechenov in 2008, after residency of dermatovenereology in Moscow Medical Academy named after I.M. Sechenov 2008-2010, had posgraduate study at dermatology department of Sechenov Moscow State Medical University, due to Russian Federation. President Scholarship for studying abroad worked in 2011-2012 in Dermatological Clinic of Muenster University Hospital. Defended thesis in 2013 (scientific mentor A.N. Lvov, A.B. Smulevitch) «Psychogenic itch: aspects of clinical systematics, complex therapy and prophylaxis», since 2014 till now is working in department of clinical dermatovenereology and cosmetology of Moscow scientific and practical center of dermatovenereology and cosmetology. In 2015 was a scientific secretaty of 16 ESDaP congress in Saint-Petersburg. In 2017 got Michael Hoenstein Memorial Scholarship by European academy of Dermatology and Venereology. In 2017 got travel grant of international Forum for the Study of itch (IFSI) to attend 9th World congress on itch. A member of Task groups of EADV of pruritus and psychodermatology. Reviewer of JEADV, Fronties, Clinical dermatology and venereology. Member of National alyans of dermatovenereologists and cosmetologists, Moscow society of dermatovenereologists and cosmetologists named after A.I. Pospelov, Member of EADV, Member of ESDaP, Member of ISD, Member of IFSI, Member of DDG, Member of EAAD. Coauthor of IFSI-guideline of prurigo. In 2016 paricipated in clinical Study of EADV — validation of itch questionnares for patients (organized by S.Staender), and in 2017 in European Prurigo Project by EADV. Secretary of Local ethics committee. Author of more than 30 publications. Speaker of local and foreign conferences and congresses.