Title : Improvement of facial beauty by a non-invasive cosmetic approach using a miniprotein
Abstract:
One of the most easily recognized aspects of beauty is the shape of the face, which can convey age, gender, and attractiveness. In women, an oval facial shape is considered attractive; however, this structure is significantly altered with age due to skin laxity. One solution to preserve or restore an oval face shape is the use of dermal fillers as an invasive aesthetic approach. In our work, we propose a non-invasive cosmetic alternative based on the topical application of a miniprotein. The objective of this work was to demonstrate the efficacy of this miniprotein to preserve and/or restore the aesthetic aspects of the faces of aged panelists. A double-blind, vehicle-controlled, split-face clinical trial was conducted on 30 healthy Caucasian women before and after 14 days, 1 month, and 2 months of topical product use. The oval face improvement parameter was determined by volume reduction measurement determined by clinical grading assessment coupled to quantitative measurements and by 3D image illustrations (Lifeviz Mini). The study's results confirm the efficacy of the miniprotein in reversing visible signs of skin aging on the face. The clinical grading of oval shape showed that after two months of miniprotein application, the percentage of subjects without an increase in assigned score was higher than the vehicle group, and the percentage of subjects that maintained the score was higher in the active ingredient group. The quantitative measurements confirmed the improvement of oval face. These results demonstrate the ability of the miniprotein to combat the aging process. These outcomes were further substantiated by 3D images.
