Title : LaMiNa: A synergistic, multimodal approach to facial rejuvenation
Abstract:
As more patients pursue facial rejuvenation treatments, an increasing number of innovative procedures are emerging in the market. Popular options typically focus on single-modality treatments for fine lines and wrinkles, such as microneedling or ablative CO2 lasers, often combined with topical biologic applications. Historically, the thermal and mechanical skin injury created by combined treatment with microneedling and ablative CO2 lasering have been considered to traumatic to the skin. However, when these modalities are paired with the powerful repair and regenerative properties of autologous nanofat, the LaMiNa procedure effectively addresses fine lines and perioral rhytids with the added benefit of a faster recovery. We investigated the safety and efficacy of co-terminus CO2 lasering and microneedling with the addition of autologous nanofat to resolve fine lines and facial rhytids. Twenty-three patients underwent facial CO2 lasering and microneedling with immediate application of autologous nanofat (LaMiNa). On verbal report, all patients reported significant resolution of perioral rhytids, negligent pain, and an average recovery period of 5 days. Histological tissue analysis showed complete recovery of the epidermis and significant reduction of perineural inflammation. We demonstrate multimodal, triple therapy with ablative CO2 lasering, microneedling, and topical application of autologous nanofat (LaMiNa) effectively treats fine lines and facial wrinkles with the benefits of a pain free, accelerated recovery.
