Title : Use of noninvasive OCT images and vibrational information to follow the effects of skin rejuvenation
Abstract:
Vibrational Optical Coherence Tomography (VOCT) is a non-invasive optical technique. It uses infrared light reflection and changes in tissue structure induced by elastic vibrations using acoustic sound. This produces images and resonant frequency measurements to follow changes in skin structure in real time. The technique produces a color-coded image based on light reflections from the cells in the different layers of the epidermis, as well as from the papillary dermal collagen, and from any fibrotic tissue present. The images from these layers are converted into measurements of elastic modulus based on determination of the resonant frequencies of each layer. While the blood vessels cannot be seen in these images the resonant frequency peak height for blood vessels can be measured. The talk will contain information on the changes in OCT images and resonant frequency measurements on skin after treatment with different skin rejuvenation techniques including needling, salicylic acid, and other topical preparations. While normal skin contains peaks at 50 Hz (cells), 100 Hz (papillary collagen), and 150 Hz (blood vessels) the height of these peaks is altered by different treatments. By breaking the grey-scale OCT images into low, medium, and high intensity pixels, the cellular and collagen contents of the treated skin can be quantitatively analyzed as well as the location of newly deposited collagen.
