Yasser Mohammed Hassanain Elsayed, Speaker at Dermatology Conferences
Egyptian Ministry of Health, Egypt
Title : Yasser's triple discoloration sign in Hall-Hittner syndrome post-recent successful ablation of WPW syndrome and neonatal closure of PDA- A new diagnostic sign and interpretation

Abstract:

Introduction: Hall-Hittner syndrome and its synonym; CHARGE syndrome is described as neurocristopathy with mutations in CDH7.  Major and minor criteria are included in the diagnosis of CHARGE syndrome or Hall-Hittner syndrome. Wolff-Parkinson-White (WPW) syndrome is a common pattern of pre-excitation with abnormal accessory pathways (AP). Patent ductus arteriosus is a frequent congenital cardiac defect due to a delay in the closure of the ductus arteriosus of birth.

Case presentation: A young mentally retarded student female girl patient presented to the physician outpatient clinic for periodic follow-up in previously published and diagnosed (CHARGE syndrome hallmarked with Wolff-Parkinson-White syndrome and patent ductus arteriosus; 20 years post-repairing is an extreme combination). Ablation of accessory pathway, ECG, echocardiography, and duplex ultrasound were the interventions.

Conclusion: The "Yasser's triple discoloration sign (Triple color sign)" in Hall-Hittner syndrome post-recent successful ablation of WPW syndrome and neonatal closure of PDA is a new diagnostic dermatological and cardiovascular sign. The mechanism of "Yasser's triple discoloration sign (Triple color sign)" is still not understood despite the suggested theories. The evidence of previously described infantile ECG Tee-Pee signs of hypocalcemia and adult low-ionized calcium may be a guide for associated DiGeorge syndrome. With the entrance of this new Sign (S), the old Mnemonic (CHARGE) syndrome can be modified to CHARGES syndrome by adding the letter (S) to it. Furthermore, future research will be recommended.

Biography:

Dr. Yasser Mohammed Hassanain Elsayed; A scientist, critical care physician, cardiologist, and independent researcher at Egyptian Ministry of Health. Publicized articles; (153). Innovations and patents (22); (3) "Yasser’s sign", (6) "Yasser’s phenomenon", (1) "Yasser’s modification", (1) "Yasser’s maneuver", (1) “Yasser’s method”, (1) “Yasser’s test”, (4) “Yasser’s syndrome”, (1) "Yasser’s fibrillation", (1) "Yasser’s Procedure", (1) Yasser’s ECG palpitations wave, (1) Factitious Yasser's Infarction, and (1) "Yasser’s Criterion". International Speaker with presentation (Conferences); (34). Accepted abstracts in Conferences with no presentation (28). Reviewer; (309) articles for (102) Journals. Honorable editor; (275) Journals. International Conferences OCM; (13). Instructor; (12) official and (118) non-official. COVID-19 publicized articles; (50). Prizes nomination; Breakthrough Prize, Einstein Prize, Abdul Hameed Showman Award for Arab Researchers, and ESICM Awards. Excellence certificates (more than 176). The most famous articles are; 1. Wavy triple an electrocardiographic sign (Yasser’s sign). 2. Wavy double an Electrocardiographic sign (Yasser’s sign). 3. Graded phenomenon (Yasser’s phenomenon). 4. Connected aircraft squadron electrocardiographic sign (Yasser’s sign). 5. Electrocardiographic Passing phenomenon (Flying phenomenon or Yasser’s phenomenon). 6. Movable weaning off an electrocardiographic phenomenon (Yasser’s phenomenon of hypocalcemia). 7. Yasser’s COVID-19 discrepancy phenomenon. 8. Yasser’s maneuver in the psychogenic coma. 9. Yasser’s modification or oxygen test. 10. Three and one method (Yasser’s method). 11. Yasser's stressor test (Fear and calm test). 12. Triphasic Yasser's stressor syndrome (Fear, calm, and fear syndrome). 13. Right to left angina Yasser’s syndrome (Swinging Yasser’s central heart syndrome) or Dancing Yasser’s heart syndrome. 14. Sinusoidal atrial fibrillation (Yasser’s fibrillation). 15. Yasser’s triple discoloration sign. 16. Yasser’s procedure. 17. Yasser's Wenckebach reversal phenomenon. 18. Yasser’s cup of coffee stress syndrome (Single cup of coffee stress syndrome). 19. Yasser’s ECG palpitations wave. 20. Bilobed apical floating heart Yasser’s syndrome. 21. Factitious Yasser's Infarction. 22. Yasser’s Criterion of Inferior ST-Segment Discrepancy Deviations in AF.

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