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Sophia Kivelitz, Speaker at Dermatology Conferences
Technical University Munich, Germany
Title : 3-D analysis of fat graft survival in reconstructive breast surgery


In Dermatological surgery and Plastic surgery Lipofilling is a common method to optimize surgical results in terms of reconstruction. Aside from its application on the entire body surface Lipofilling is particularly established in breast surgery.

Since breast cancer is still the leading cause of death among women and up to one third of patients undergo mastectomy, multiple techniques of breast reconstruction are highly relevant (1,2).  Subcutaneous fat is biocompatible, easily accessible (3,4,5) and causes less allergic reaction and granuloma as non-autologous materials (3, 6, 7, 8, 9). In order to do justice to the shape and volume of the female breast in its natural complexity, Lipofilling represents a both simple and effective surgical option. It offers the possibility to restore or enhance volume, correct defects and asymmetries and improve contours.

Lipofilling usually consists of the following steps: the fat harvesting through liposuction, the preparation by centrifugation and the transplantation of the purified lipoaspirate with slim cannulas in various layers at the recipient site. Donor sites are mostly abdomen, flanks or thighs.

Current discussions on Lipofilling engage particularly in the oncological safety of the method as well as in fat graft survival. The prediction of the required injection volume poses a significant challenge in the process of Lipofilling. Which technique of fat harvesting, processing and injection is the most effective? And what parameters may possibly compromise the engraftment of the injected fat? 

In this study, a statistical analysis of breast volume and lipid retention was made, to show the overall effect of Lipofilling as well as possible effects on increased or decreased resorption rates. By using 3D imaging and measuring tools, breast volumes were calculated before and at five follow up dates after Lipofilling.

The aim of this project was to develop a technique of evaluation in order to quantitatively measure the breast contour change after surgery. The exact calculations of post operative volumes may significantly improve the outcome of the treatment and increases its predictability.


MS Sophia Elisa Kivelitz studied Human Medicine at the Technical University, Munich, Germany and graduades as MD in 2017. She joined the research group (CAPS-Computer assisted plastic surgery) of Dr. med. Maximilian Eder in the department of Plastic surgery and Hand surgery at Klinikum Rechts der Isar, Technical University Munich. From 2015 until 2021 patients data from fat grafting surgeries was analyzed in terms of fat graft survival and possible limiting factors.