Title : A demonstrative case series on prophylactic treatment of post excised keloids with topical imiquimod
Importance: Keloid excision alone can have recurrence rates approaching 80%.
Objective: To evaluate the clinical use of topical Imiquimod in prophylaxis of keloid regrowth post keloid excision.
Design, Setting, and Participants: Our study is a retrospective case series involving 6 patients with auricular keloid (lobule or helix) present from months to years who were treated at Las Vegas Dermatology from 2006 to 2022.
Results: All 6 patients had normal wound healing post-keloid excision with zero recurrences.
Conclusion and Relevance: Little is known about Imiquimod efficacy for keloid growth prophylaxis. Our study demonstrates that Imiquimod 5% topical applied nightly for six weeks post keloid removal is well tolerated resulting in prophylactic treatment of keloid recurrence.