Title : A real-world study to evaluate the effectiveness of a moisturizing cream as an adjuvant in the treatment of Eczema
Abstract:
Introduction
Eczema is a group of papulosquamous diseases in skin and has various types. It is a common skin condition marked by itchy and inflamed patches of skin. The main symptom of eczema is itchy, dry, rough, flaky, inflamed, and irritated skin. It can flare up, subside, and then flare up again. Eczema can occur anywhere but usually affects the arms, inner elbows, backs of the knees, or head (particularly the cheeks and the scalp). It is not contagious, and, in some cases, becomes less severe with age. Moisturizers play an important role in the management of several skin disease as an adjunct therapy.
Methods
In this 2-group, real world setting study, one group received a moisturizer- Venusia Max Cream to be used as adjuvant, along with prescribed treatment, whereas the other group received only the prescribed treatment (steroids) prescribed by Investigator. The primary objective was to evaluate the moisturizing efficacy of Venusia Max Cream when used as an adjuvant to the main line of treatment for eczema. The evaluation criteria included significant reduction in EASI (Eczema Area and Severity Index) scores, measuring skin hydration using MMSC (Moisture Meter-SC), reduction in itch score and reduction in burning sensation.
Results
At the end of the study at 4 weeks, 113 out of the 120 patients enrolled completed the study. In the group with Venusia Max cream, significant reduction in the EASI score as compared to the baseline; significant increase in skin hydration as compared to baseline and to the comparator group where Venusia Max Cream was not used; significant reduction in itching score as compared to baseline and to the comparator group where Venusia Max Cream was not used along with treatment; and significant reduction in burning sensation was recorded.
Conclusion
Venusia Max Cream improved the skin hydration significantly on eczematous skin of patients and significantly reduced the itching score compared to the group of treatment where Venusia Max Cream was not used.
