Title : Meta-analyses about tranexamic acid in the treatment of melasma
Abstract:
This lecture will talk about the use of tranexamic acid for the treatment of melasma.
Melasma is a prevalent and chronic disease which we don’t know the exact mechanism of action. There are a lot of stimuli to provoke it, for example: sun, hormones, stress, heat, local trauma and skin irritation.
Tranexamic acid is an antifibrinolytic drug that prevents the transformation of plasminogen into plasmin, thus avoiding all the provocative stimuli.
The dosage we use systemic tranexamic acid to treat melasma is 500mg once a day during four to six months.
We have just finished a meta-analysis study, and I will comment the results.