Abstract:
Chronic, non-healing diabetic wounds put a massive economic burden on health services causing patient incompliance and discomfort. Thorough interpreting of chronic wound pathophysiology led to the fabrication of targeted systems of drug delivery that can improve and accelerate the wound healing process. Natural polymers or biopolymers are now explored for the fabrication of wound dressings. Hence, in this review article, the pathophysiological aspects of chronic wounds, current treatment approaches, and potential biomaterials employed for treating wounds are explicated. The main emphasis is on biopolymers which aid in creating innovative systems based on nanotechnology for effective skin generation in chronic wounds.
Biography:
Dr. Madhu Gupta is working as an Associate Professor in Delhi Pharmaceutical Sciences and Research University, New Delhi. She is pioneer scientist in the field of nanotechnology and drug delivery field. Dr. Madhu Gupta has research experience pertaining to drug delivery to nanoformulations for placental extract, regenerative medicine, magical molecule delivery, bioligands for targeting of bioactives and drug moiety, biopolymers, She is exploring the area of fungal infection, wound healing, diagnostic devices, PK-PD modelling, herbal delivery and psoriasis. Dr. Gupta recognized among the top 2% of scientists globally in the year 2023-24, list that often comes from data compiled by Stanford University researchers, published in collaboration with Elsevier and other academic databases. She has over 100 research publications to her credit published in journals of high scientific impact and contributed 30 chapters in various renowned books and to several international and national books.