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Monica Trifitriana, Speaker at Dermatology Conferences
Sriwijaya University, Indonesia
Title : The best efficacy treatment for alopecia androgenetic: A systematic Review and Meta-Analysis


Androgenetic alopecia (AGA), is a genetically predetermined disorder due to an excessive response to dihydrotestosterone (DHT). Currently, non-surgical treatment of androgenetic alopecia is more in demand by patient. There are many non-surgical treatments, ranging from topical treatments, oral medications, and procedure treatments.We aim to assess the latest evidence of the efficacy of non-surgical treatments of androgenetic alopecia in men comparison to placebo for improving hair density, thickness, and growth.We performed a comprehensive search on topics that assesses non-surgical treatments of androgenetic alopecia in men from inception up until November 2021.There were 24 studies out of a total of 2438 patients divided into five non-surgical treatment groups to assess the effectiveness of hair growth, namely: minoxidil 2% (MD: 8.11 hairs/cm2), minoxidil 5% (MD: 12.02 hairs/cm2), low-level laser light therapy/LLLT (MD: 12.35 hairs/cm2), finasteride 1mg (MD: 20.43 hairs/cm2), and Platelete-Rich Plasma/PRP  with microneedling (MD: 26.33 hairs/cm2). All treatments had significant results for increasing hair growth particularly in cases of androgenetic alopecia in men (P<0.00001).

Conclusion: From the results, it was found that the five non-surgical treatment groups proved to be effective and significant for hair growth, particularly in cases of androgenetic alopecia in men. In order of the best non-surgical treatment for hair growth starting from PRP with microneedling, Finasteride 1mg, LLLT, minoxidil 5%, to minoxidil 2%.


Dr. Monica studied about medicine at Sriwijaya University, Indonesia and graduated as MD in 2019. She then joined the research group with any of consultant doctors in indonesia. She received her scholarship from LPDP to continue her study. Nowadays, She has published 10 research articles in journals based on scopus.