Title : Personalized and precision medicine as a unique avenue to have the healthcare model renewed to secure the National Biosafety: Towards individualized cosmetics, reconstructive plastic surgery and the beauty of the future to come?
Abstract:
Topical problems in cosmetic and plastic medicine and surgery: Dozens of cosmetics and skin care products are suspected to provoke allergic reactions. This ambiguity encourages the development of particular tools to assist in product individualization, which has thrived among cosmetic companies. Usually cosmetic companies create health, wellness and beauty products for consumers, based on its proprietary genome-, phenome- and exposome-based testing.
For instance, developed by the L’Oréal, the Perso smart skincare system is capable of providing individualized skincare solutions via a four-step process taking into account the specificities of the user’s skin, local weather conditions, and the user’s product preferences.
L’Occitane en Provence is also betting on personalized beauty with Duolab, an innovation comprising a device, a range of capsules - including three moisturising bases and five targeted concentrates - and a skin predictive diagnostic tool. The tool assesses individually the customer’s skin requirements and generates a personalized care protocol.
Amorepacific presented a 3D face mask printing system coupled with the 3D printing system developer Lincsolution. The latter uses a smartphone app to instantly measure individual users’ facial dimensions and print a personalized hydrogel mask that caters to individual facial features and skin conditions.
Envision a world where your face cream is tailor-made for your DNA, your hair mask knows you got highlights the last 5 years, and your serum has a better handle on your likes, your dislikes - even what you had for breakfast - than your partner. Innovators from the worlds of precision biotech and unique beauty are dreaming up those personalized beauty products right now, and they’ll be in our hands soon.
In the wellness sphere, precision tests are also used to define slow or fast metabolizers. While genomic-based customized nutrition is being implemented, personalized diets might lack sufficient evidence for full integration into the full-set cosmetic setting. The concept of PPM-based nutriogenomics is to provide accurate nutritional recommendations for an individual to obtain a healthier lifestyle. Those advances are paving the way for the design of innovative strategies for the control of chronic diseases and obesity, in particular. Personalized nutrition has the huge potential to maintain health and wellness due to the rigorous nutrigenomic analysis whilst considering the genetic makeup of an individual. So, in a more distant future, the new cosmetic and nutritional brands like would create unique shampoos, conditioners, masks and personalized diets based on your individualized answers and data being harvested from your genetic passport.
Dermatology and cosmetology require doctors to make treatment decisions based on patient self-reporting, which poses challenges including patient recall or recognition of exacerbating factors, leading to a trial-and-error approach to management and additional consultations. Meanwhile, a lack of particular guidelines is the predominant barrier for adoption, indicating a need for the development of best practices and guidelines to support the implementation of PPM. So, the implementation of PPM requires a lot before the current model “physician-patient” could be gradually displaced by a new model “medical advisor-healthy person-at-risk”. This is the reason for developing global scientific, clinical, social, and educational projects in the area of PPM to elicit the content of the new branch.
