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The introduction of PPM-guided tools has benefits for multiple stakeholders; patients benefit by having improved outcomes, physicians can make confident decisions in managing their patients, and the healthcare system saves significant dollars through the reduction of wasted spend [....] » Read More
Background: Non-surgical facial lifting has become increasingly popular due to its minimal invasiveness and reduced recovery time compared to surgical methods. Among various natural fillers, autologous plasma gel derived from the patient's own blood has gained attention as a [....] » Read More
Background: Androgenetic alopecia (AGA) is the most prevalent form of hair loss in men, yet current FDA approved treatments finasteride and minoxidil exhibit limited efficacy and are often associated with undesirable side effects. This underscores the urgent need for novel therap [....] » Read More
Background: Hypertrophic and unesthe4c scarring remains a major concern in aesthe4c and dermatologic prac4ce. Conven4onal measures such as silicone or cor4costeroids show inconsistent benefit and lack standardized protocols. Botulinum toxin A (BoNT-A) has emerged as an adjunct t [....] » Read More
Background: Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disease with increasing prevalence in children. Recent studies suggest a possible link between systemic metabolic abnormalities like dyslipidemia and the severity of AD, but data in pediatric populations [....] » Read More
Accurate diagnosis and clinical vigilance are vital in complex dermatology. Generalized pruritus (itching) without visible skin lesions is often dismissed as benign but can signal hidden malignancies. Studies show patients with chronic pruritus have up to six times higher odds of [....] » Read More
Introduction: The skin microbiota contributes to skin health. Skin aging results from intrinsic and extrinsic factors that alter the structure and functions of the skin. Recent studies reveal that the skin microbiota plays a key role in this process. Objective: The objective of [....] » Read More
Carcinoma en cuirasse (CeC) is an uncommon form of cutaneous metastases of breast cancer, characterized by diffuse sclerodermoid induration of the skin and the skin of the chest wall is studded with carcinomatous indurated plaques. CeC can mimic postirradiation morphea, inflammat [....] » Read More
Introduction: Blau syndrome is a rare autosomal dominant granulomatous disease. The cardinal signs of this condition are a triad of skin rashes, arthritis, and uveitis. However, the discovery of CARD15 mutations as being at the origin of this syndrome has made it possible to broa [....] » Read More
Introduction: Calciphylaxis is a disease in which metastatic calcification affects small and medium-ships, resulting in significant dermatological manifestations. The lesions typically occur in areas of high fat content and gradually progress to pressure sores. We report a case o [....] » Read More
Introduction: Leishmaniasis is a parasitic disease that can manifest as skin, mucosal, mucocutaneous, and visceral disorders. The cutaneous form is the most prevalent and endemic in the Mediterranean region, while the mucocutaneous form is exceptionally rare, with only a few repo [....] » Read More
Background: Onycholysis (separation of nail plate from bed) can be primary (idiopathic) or secondary. Aims & Objectives: This observational, cross-sectional study estimated the frequency of various etiological factors in patients presenting with onycholysis, based on clinical [....] » Read More
Background: Melasma is a chronic, relapsing hyperpigmentary disorder that poses significant therapeutic challenges. Tranexamic acid (TA), an antifibrinolytic agent with anti-melanogenic and anti-angiogenic properties, has recently gained attention as an effective treatment option [....] » Read More
The evolution of thread lifting technology has reached a pivotal milestone merging three core dimensions of facial rejuvenation into a single intervention: mechanical lifting, volume restoration, and true biostimulation. This presentation introduces the latest generation of Aptos [....] » Read More
There are many types of skin diseases, ranging from eczema to psoriasis, to acne, all of which are known to greatly impact mental health. The goal of this study is to show the effect of skin disorders on mental health by reviewing primary source articles found on a variety of rep [....] » Read More
Alopecia areata incognita (AAI), a rare and often underrecognized variant of alopecia areata, presents as diffuse, acute-onset telogen hair shedding without the classic well-demarcated patches of hair loss. The pathogenesis of AAI is thought to involve autoimmune targeting of ana [....] » Read More
Melanoma remains one of the most aggressive forms of skin cancer worldwide. Participation in clinical trials is critical for the advancement of new treatments. However, equitable access to therapies depends on the geographic distribution of clinical trial sites. Disparities in tr [....] » Read More
Background: Artificial intelligence (AI) and teledermatology are transforming clinical practice, enabling clinicians to upload patient photographs into applications that can guide differential diagnosis. While these tools are valuable, dermatology remains a specialty where subtle [....] » Read More
Introduction: Melasma is a prevalent acquired pigmentary disorder characterized by hyperpigmented macules or patches with irregular borders. This study aimed to evaluate the efficacy of tranexamic acid (TXA) in treating melasma through a meta-analysis and systematic review of ran [....] » Read More
Today, there is an increasing number of skin diseases, so early detection of skin diseases is one of the top priorities worldwide. Ultraviolet radiation and tanning beds are the main risk factors. Early detection of skin lesions is currently a priority task worldwide. It has been [....] » Read More
Rationale: Hypertensive crisis is a serious cardiovascular problem. Refractory and resistant severe hypertension is sometimes needed for an urgent clinical diagnostic assessment for the cause. Hypertensive crisis due to pheochromocytoma is a rare problem but has an association wi [....] » Read More
Background and aim: Cosmetic and skincare products are widely consumed worldwide, often exposing users to chemical compounds with potential health risks. In Sudan, the misuse of therapeutic drugs such as corticosteroids, cyproheptadine, and prednisolone for cosmetic purposes has [....] » Read More
Background: Alopecia areata (AA) is a chronic, relapsing autoimmune disorder targeting the hair follicle. Its clinical spectrum ranges from patchy alopecia to total hair loss (alopecia totalis or universalis), with variable progression and recurrence. While a genetic predispositi [....] » Read More
Background: Terra firma-forme dermatosis (TFFD) is a benign yet frequently underdiagnosed cutaneous condition characterized by asymptomatic, dirt-like hyperpigmented plaques caused by retained keratinization. While commonly seen in children and typically affecting intertriginous [....] » Read More
Introduction: Toxic shock syndrome (TSS) is a rare, life-threatening illness caused by toxin-producing Staphylococcus aureus or Streptococcus pyogenes. Bullous cutaneous manifestations are uncommon and may resemble autoimmune blistering diseases, leading to delayed recognition. [....] » Read More
Introduction: Giant congenital melanocytic nevus (GCMN) is a rare cutaneous malformation present at birth, characterized by extensive melanocytic proliferation. Its clinical relevance lies in the potential for malignant transformation and association with neurocutaneous melanosis [....] » Read More
This study aimed to develop an antioxidant slimming cream using coffee grounds and its cosmetic oil, and to evaluate their anti-obesity potential in vivo through dietary incorporation in rats. The aqueous extract of coffee grounds was prepared using the maceration method, a soli [....] » Read More
Title : Modern non-invasive methods for in vivo assessment of skin
Georgios N Stamatas, SGS, France
Recent innovations in spectroscopy and microscopy techniques have enable detailed chemical, structural, and functional analysis without the need for biopsy. The concept of optical biopsy has become a reality allowing clinicians and researchers to obtain molecular and morphologica [....] » Read More
Title : Paraneoplastic autoimmune multiorgan syndrome or PAMS: Paraneoplastic pemphigus revisited
Sergei A Grando, University of California Irvine, United States
Paraneoplastic autoimmune multiorgan syndrome (PAMS) is characterized by a heterogenous group of signs and symptoms including severe desquamative stomatitis, a polymorphous cutaneous eruption, humoral immunity against plakin proteins, contribution of cell-mediated autoimmunity an [....] » Read More
Title : Personalized and precision medicine as a unique avenue to have the healthcare model renewed to secure the national biosafety: Advanced skincare solutions in individualized cosmetology, reconstructive plastic surgery and the modern beauty
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
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Title : Comparative efficacy of omalizumab and dupilumab in children with Chronic Spontaneous Urticaria (CSU): A retrospective cohort analysis
Molynna Nguyen, University of Toledo, United States
Background: Chronic spontaneous urticaria (CSU) is a mast cell-driven disease characterized by wheals and/or angioedema persisting more than six weeks. Although well-studied in adults, CSU remains under-studied in pediatric populations. This study aimed to compare the efficacy of [....] » Read More
Title : Rare skin diseases in Vietnam
Tran Hau Khang, National Hospital Dermatology and Venereology, Vietnam
A rare disease is as a condition that affects very few people. According to data from the National Organization for Rare Disease (NORD), there are more than 7000 rare diseases and the total number of people living with a rare disease is estimated at 300 millions including c [....] » Read More
Title : Antifungal resistance in dermatophytes: A growing concern
Jannatul Sharmin Joarder, Dhaka Medical College Hospital, Bangladesh
Dermatophytes are a group of keratinophilic fungi responsible for superficial infections of the skin, hair and nails collectively known as dermatophytosis.In recent years, there has been a notable rise in antifungal resistance among dermatophyte species, posing a significant publ [....] » Read More
Title : CO2 laser labiaplasty vs. conventional surgical labiaplasty: A comparative clinical approach in outpatient practice
Benosman Sihem, Societe Algerienne De Medecine Esthetique , Algeria
Labiaplasty has gained increasing attention as part of intimate aesthetic and functional genital rejuvenation. Traditionally performed using scalpel-based surgical techniques, this procedure is now evolving with the integration of laser technology. This presentation aims to compa [....] » Read More
Title : Beyond the mirror
Ejigayehu Kassa, Laba Media and Communications Addis Abeba, Ethiopia
This research offers a paent-expert perspecve on the profound psychological journey accompanying chronic, visible dermatoses. Moving beyond tradional clinical definions of "cure," this research invesgates the crical, yet oen unaddressed, process of psychosocial healing [....] » Read More
Title : "Mirror mirror on the skin” — A low-cost community strategy to reduce melanoma disparities in Washington, D.C.
Kayla Sampson, Georgetown University School of Medicine, United States
Melanoma remains a preventable yet deadly cancer whose outcomes are disproportionately worse among African Americans, particularly in Washington, D.C., where late-stage diagnoses and higher mortality are concentrated in underserved Wards 7 and 8. Despite lower overall incidence, [....] » Read More
Title : Keratinocyte apoptosis by caspase – 3 Immunostaining in histopathology as marker of activity as well as correlation with dermoscopy findings in Cutaneous Lupus Erythematosus (CLE) in skin of color: An observational study.
Subhojit Ray, All India Institute of Medical Sciences, India
Background: Keratinocyte apoptosis is involved in pathogenesis of CLE, but the same as a marker of disease activity is not established in literature. Aim & Objective: To correlate keratinocyte apoptosis stained with Caspase 3 immunostaining with R-CLASI activity (R-CLASI-A [....] » Read More
Title : Ethnic differences in biologic therapies for atopic dermatitis
Dalia Al Temimi, Barts and The London School of Medicine and Dentistry, United Kingdom
Introduction & Objectives: Atopic dermatitis is the most prevalent skin condition globally and has become a significant public health concern due to its impact on quality of life. In recent years, the introduction of biological therapies has revolutionised care by targeting s [....] » Read More
Title : Dermatitis passivata: Unfolding the layers of self neglect
Surajbala Khuraijam, Manipur Health Services, India
Introduction: Diogenes syndrome is mostly seen in geriatric or demented patients. It is a behavioural disorder characterized by self neglect, social withdrawal, poor personal and domestic hygiene. A milder form of this is dermatitis passivata. Dermatitis passivata is a psychoderm [....] » Read More
Title : Exclusive cutaneous form of rosai-dorfman disease : Two case reports
Chalouli Lamia, Military Hospital of Algeria, Algeria
Introduction: Rosai-Dorfman disease (RDD) is a rare, benign non-Langerhans cell histiocytosis primarily affecting the lymphnodes, practically those in the cervical region. Cutaneous involvement is common and can be an initial indicator of the disease. However, diagnosing RDD base [....] » Read More