Sergey Suchkov, Speaker at Dermatology Conference
N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : Personalized and precision medicine as a unique avenue to have the healthcare model renewed to secure the national biosafety: Advanced skincare solutions in individualized cosmetology, reconstructive plastic surgery and the modern beauty

Abstract:

This strategy of Personalized and Precision Medicine (PPM) as an upgraded model of healthcare would give a real opportunity to secure preventive, prophylactic, therapeutic and rehabilitative measures whose personalization could have a significantly positive influence on demographics. The evolution of PPM-guided biodesign in dermatology signifies a transformative shift towards individualized treatments, driven by the integration of biomarkers, which serve beyond diagnostics, offering insights into disease staging, prognosis, and therapeutic monitoring.

Regarded as innovators and early adopters, aesthetic dermatologists, cosmetologists and plastic surgeons stand at the forefront of novel medical advancements, incorporating new technologies into their practice with ease. For instance, skin nanobiosensors are already used in the cosmetics industry, or moisture sensors to measure their skin hydration. For instance, developed by the L’Oréal, Perso smart skincare system is capable of providing individualized skincare solutions via a four-step process taking into account the specificities of the user’s skin, local weather conditions, and the user’s product preferences. Amorepacific presented a 3D face mask printing system coupled with the 3D printing system developer Lincsolution, that uses a smartphone app to instantly measure individual users’ facial dimensions and print a personalized hydrogel mask that caters to individual facial features and skin conditions. P&G Ventures, the startup studio within Procter & Gamble, returned to CES 2020 to showcase the development of Opte Precision Skincare System. This personalized handheld inkjet printer can instantly make the appearance of skin’s hyperpigmentation disappear and fade spots over time.

The market for skin sensors technologies will reach $275 million by 2030! In tandem with digitization comes the demand for personalization. Skin sensors would play a crucial role soon - both in helping the consumer quantify changes that are imperceptible to the naked eye, but also with the possibility of sending valuable big data back into profiled research and targeted development for the next generation of products. Being cosmetologists, you must be prepared for the integration of patient and system factors.

The integration of AI technology and the capture of Big Data techniques should foster the next great leaps in cosmetic medicine and plastic surgery as segments of the Art Medicine, allowing you to capture the de-tailed minutiae of PPM. In the future, precise monitoring of patient imaging photographs may allow surgeons to monitor post-operative progress with real-time updates and save patients an in-person visit. Meanwhile, although such technologies are not yet available in plastic surgery, there is significant potential for AI-assisted plastic and reconstructive surgery in the near future to come.

The progress in active components and ingredients has boosted the derma-pharmaceutical and cosmetic fields by allowing formulations to display enhanced skin permeation capabilities. Of special interest is the introduction and incorporation of biodesign-inspired nanotechnology-based approaches into cosmetics for evincing novel formulations that confers aesthetic as well as therapeutic benefits. Nanocosmetics acts via numerous delivery mechanisms, which involves nanocarrier systems, polymeric or metallic nanoparticles, nanocapsules, dendrimers, nanosponges, etc. Each of those, have particular characteristic properties, which facilitates increased drug loading, enhanced absorption, better cosmetic efficacy, and many more.

Nanocrystal technology offers consumers cutting-edge and effective products and exhibits enormous development potential in the beauty business as a new delivery method to address the issue of low solubility and low permeability of sensitive chemicals. Including nanocrystalline loaded gel and emulsion, demonstrating the beauty efficacy five aspects: anti-inflammation and acne, anti-bacterial, lightening and freckle removal, anti-aging as well as UV protection.

Cosmetology require doctors to make treatment decisions based on patient self-reporting, which poses challenges including patient recall or recognition of exacerbating factors, leading to a trial-and-error approach to management and additional consultations. A lack of particular medical guidelines is the predominant barrier for the adoption. Implementation of PPM. So, just keep you on the way to feel and to understand that the Grand Change and Challenge to secure our health and wellness are rooted not in Medicine, and not even in Science! Just imagine WHERE? In the upgraded Hi-Tech Culture! Only Creative Minds would be able to Re-Imagine Healthcare, to Transform Procedures and Prescriptions, and to Augment Physician Capabilities. This approach (PPM) mentioned should be based on postulates which will change the incarnate culture and social mentality!

While challenges persist, the future holds promise with the integration of IT algorithms and nanotechnology for real-time monitoring. With biomarkers at the forefront, dermatological and cosmetological care is poised for further optimization, ultimately enhancing therapeutic efficacy and improving patients’ quality of life. Overall, PPM-driven dermatology and cosmetology has the potential to provide a more comprehensive understanding of skin conditions at the individual level and improve patient outcomes.

Biography:

Sergey Suchkov was born in the City of Astrakhan, Russia, in a family of dynasty medical doctors. In 1980, graduated from Astrakhan State Medical University and was awarded with MD. In 1985, Suchkov maintained his PhD as a PhD student of the I.M. Sechenov Moscow Medical Academy and Institute of Medical Enzymology. In 2001, Suchkov maintained his Doctor Degree at the National Institute of Immunology, Russia. From 1989 through 1995, Dr Suchkov was being a Head of the Lab of Clinical Immunology, Helmholtz Eye Research Institute in Moscow. From 1995 through 2004 - a Chair of the Dept for Clinical Immunology, Moscow Clinical Research Institute (MONIKI). In 1993-1996, Dr Suchkov was a Secretary-in-Chief of the Editorial Board, Biomedical Science, an international journal published jointly by the USSR Academy of Sciences and the Royal Society of Chemistry, UK. At present, Dr Sergey Suchkov, MD, PhD, is: Professor, and Chair of the Dept for Personalized Medicine & Precision Nutriciology of the Institute for Global Health of RosBioTech, and Professor of Dept of Clinical Immunology, A.I. Evdokimov Moscow State Medical and Dental University (MGMSU), Russia; Secretary General, United Cultural Convention (UCC), Cambridge, UK. Dr. Suchkov is a member of the: New York Academy of Sciences, USA, American Chemical Society (ACS), USA; American Heart Association (AHA), USA; European Association for Medical Education (AMEE), Dundee, UK; EPMA (European Association for Predictive, Preventive and Personalized Medicine), Brussels, EU; ARVO (American Association for Research in Vision and Ophthalmology); SER (International Society for Eye Research); Personalized Medicine Coalition (PMC), Washington, DC, USA

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