Title : Carcinoma en cuirasse: A rare cutaneous metastasis of breast carcinoma
Abstract:
Carcinoma en cuirasse (CeC) is an uncommon form of cutaneous metastases of breast cancer, characterized by diffuse sclerodermoid induration of the skin and the skin of the chest wall is studded with carcinomatous indurated plaques. CeC can mimic postirradiation morphea, inflammatory breast cancer, radiation dermatitis, herpes zoster and other cutaneous metastases. We reported a female of 28 years with a prior history of right breast invasive ductal carcinoma 2 years back. At the initial phase she was diagnosed as invasive intraductal carcinoma (T2, N2, M0 and HER2/ ER/PR negative) with history of modified radical mastectomy followed by chemo and radiotherapy. 2 months back she developed painful plaque over right chest wall. Histopathology of the lesional skin biopsy from the plaque was consistent with invasive ductal carcinoma. Patient had metastatic lesion on left axillary lymphnodes at the same time and was referred to Medical oncology department where she was treated with Gemcitabin and Cisplatin. Any unexplained skin changes in breast cancer patients should be considered as carcinoma en cuirasse. Many advanced therapeutic options are available for metastatic breast cancer. Based on this case, the patients with this disease may have better outcomes.
