Title : Exploring an enigmatic role of chemical peels in nail disorders and nail rejuvenation
Abstract:
In recent times, there is an increased awareness about the appearance of nails. Due to conditions like psoriasis and use of nail grooming procedures the incidence of rough, dull and discolored nails has increased. In such patients where cosmetic results are desired, glycolic acid peel acts as a non-invasive, non-cumbersome method along with conventional management which takes time to show response.
Objective: The aim of study is to assess safety and efficacy of 70% glycolic acid for controlled keratolysis of the nail-plate, which could result in smoother and brighter nails.
Materials and Methods: A prospective single-center open-label uncontrolled study of 25 patients, 17 with dry, rough, discolored nails and 8 with hyperkeratotic nails were included in the study group. Petroleum jelly was applied on the cuticle margins and 70% glycolic acid was applied over the nail plate for 30 minutes. In dry rough discolored nails, single sitting was done while in hyper-keratotic nails multiple weekly sittings were done.
Results: Clinical diagnosis was made on the basis of nail surface changes. Evaluation was done after 2 weeks of last sittings of the procedure. Out of 25, 18 patients had onychomycosis or nail LP,psoriasis and 7 had changes due to external factors. Out of 25 patients with dry rough nails, 18(72%) Showed good improvement, 5(20%) showed average improvement and 2(8%) were non-responsive. Adverse effects were mild and tolerable. None withdrew from study.
Conclusion: Nail abnormalities can produce psychological effects like lack of self-confidence and depression. Application of glycolic acid is a safe, cheap and well-tolerated treatment modality instead of costly n cumbersome treatment like acrylic gels. It is worth further exploration, unrevealing the different role of chemical peels in nail rejuvenation and offer an opportunity to do more than just camouflage, they act by normalising the defective onychokeratinisation also.
