Dermato Endocrinology is an interdisciplinary field that focuses on the complex interactions between the skin and the endocrine system. It explores the hormonal influences on various skin functions, including growth, development, metabolism, and immune response. The skin serves as both a target and a source of hormones, with numerous receptors and enzymes involved in hormone signaling pathways. Endocrine disorders can manifest with skin-related symptoms, and conversely, skin diseases may reflect underlying endocrine dysfunction. For example, conditions like acne, hirsutism, and alopecia can be associated with hormonal imbalances, such as androgen excess. Similarly, thyroid disorders may manifest with changes in skin texture, hair, and nails. Dermato-endocrinology encompasses a wide range of topics, including the role of hormones in skin aging, wound healing, and skin cancer development. Hormonal therapies are commonly used in dermatology to manage various skin conditions, such as hormone replacement therapy for menopausal symptoms, anti-androgen therapy for acne or hirsutism, and corticosteroids for inflammatory skin diseases. Research in dermatology and endocrinology continues to uncover the intricate connections between hormones and skin health, leading to advances in diagnosis, treatment, and prevention of skin disorders. Collaboration between dermatologists, endocrinologists, and other specialists is essential for comprehensive patient care and management of dermatologic conditions with underlying endocrine implications. Understanding the interplay between hormones and the skin provides valuable insights into both dermatologic and endocrine health and opens up avenues for novel therapeutic approaches in dermatology.