Erythema Infectiosum is a mild viral infection that is more commonly known as the “slapped cheek” syndrome or Fifth Disease due to it being the fifth most common childhood disease. It is caused by human Parvovirus B19, which leads to the characteristic facial rash. Other symptoms usually include a mild fever, headaches, and aching joints in adults but these may be absent in children. It spreads easily from person to person, with the virus being released through coughing and sneezing. A person is most contagious during the early stages of the illness and remains contagious for up to 3 weeks. Most common in children, Erythema Infectiosum is easily identified by the bright red rash which appears the sufferer's cheeks. The rash can sometimes spread to the arms, trunk and legs, becoming more evenly distributed as time PC passes. It fades slowly, usually over the course of around 4 weeks, evolving into a lacy reticulated pattern. The rash is typically one of the last symptoms to occur before the infection resolves. In addition to the rash, some people with Erythema Infectiosum may experience aching and tiredness in their joints. Adults are more likely to experience this symptom than children. If joint pain does occur, it is usually mild and short-lived. Erythema Infectiosum is usually a self-limiting illness and most patients do not require any medical treatment. However, those with pre-existing conditions that make them susceptible to more serious complications may need further medical monitoring. It is important that woman who are pregnant or suspect that they may be pregnant seek medical advice as they are at greater risk of potentially serious complications. In conclusion, Erythema Infectiosum is a common viral infection that is easily spread from person to person. It is typically identified by a bright red rash that appears on the cheeks and in some cases spreads to other areas of the body. Most sufferers will not require medical treatment to recover, however pregnant women and those with pre-existing conditions should seek medical advice.