Itching is a common symptom that can occur anywhere on the body and is a frequent complaint of dermatologic patients. Itching can often be felt in the skin and associated with a prickling or crawling sensation. It can be caused by a variety of conditions, including dry skin, irritation, allergic reactions, skin diseases, and systemic diseases. The treatment for itching often depends on the cause. For dry skin, moisturization is often the first step, and daily use of creams or lotions can help improve the skin’s hydration. For allergic reactions, soothing topical agents or oral antihistamines can be used. Topical steroids are sometimes used to treat skin inflammation, and systemic medications, such as oral steroids, can be used to treat severe allergic reactions if needed. In some cases, itching can be a sign of a skin disease, such as eczema or psoriasis. In these cases, treatment may include topical and systemic therapies, such as topical steroids or immune modulating therapy, to manage the associated skin inflammation. Itching can also be caused by systemic illnesses, such as liver or kidney disease, and may require specific treatments specific to the underlying condition. Additionally, itching can be a side effect of medications, including cancer chemotherapy drugs. In these cases, the itching can often be managed through stopping or changing the medication. Itching can also be a sign of an infection, such as scabies, head lice, or fungal infection. Treatment often involves the use of topical agents, and sometimes oral medications. A dermatologist can evaluate and diagnose the cause of the itching and develop an appropriate treatment plan. Overall, itching is a common complaint that can have many causes, both skin and systemic. Proper diagnosis and explanation of the cause is the key to finding an effective treatment.