Skin grafting is a wound closure procedure used most commonly in dermatology to repair wounds caused by skin cancer excision. Skin grafting is the process of transferring skin and, in certain cases, other underlying tissue types to another part of the body. Around 2500-3000 years ago, the practise of skin harvesting and transplantation was first reported. Grafting can yield an excellent cosmetic effect, although it is now less popular than flap closures. Unlike flaps, skin grafts are fully disconnected from their blood supply, whereas flaps are connected to a blood supply via a pedicle. Skin grafts are less technically challenging, but they can take more time since they produce a second surgical site. Skin grafts are most typically used to repair the skin after surgical removal of cutaneous malignancies; however, they can also be used to treat chronic nonhealing cutaneous ulcers, replace tissue lost in full-thickness burns, and restore hair to alopecia areas.
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