S kin atrophy is a major adverse effect of topical glucocorticoids and is a serious clinical problem. We recently reported that several negative regulators of Akt/mTOR signaling including REDD1 (regulated in development and DNA damage 1) and FKBP5 (FK506 binding protein 5) are st [....] » Read More
Skin needling is emerging as one of the most important, affordable ways to treat scars, lax skin, stretch marks and to rejuvenate photoaged skin. It is safe for all colours of skin and never causes permanent colour changes. Fernandes considered it the alternative to laser resurfa [....] » Read More
Changes of dermal collagen and elastin content are characteristic for skin aging as well as for pathological skin conditions. The formation of lines and wrinkles in light-exposed areas throughout the body, such as the face, throat and hands are a wellknown sign of skin aging. Bot [....] » Read More
Background: Skin toxicity is one of the most common side effects of Radiation Therapy (RT) in breast cancer patients, and is associated with increased morbidity. Almost 30% of patients receiving RT experience radiation dermatitis (RD); however, no definitive guidelines are availa [....] » Read More
The incidence (new and relapse) rate of tuberculosis in Sri Lanka in 2016 was 40.9 per 100,000 population (8332 new and 328 relapse cases). Out of 8332 diagnosed patients with TB, 2525 (30.3%) were in extrapulmonary sites. The annual risk of TB incidence at the national level rem [....] » Read More
Japanese cosmetic companies have largely stopped animal testing voluntarily and now hope that the use of new ingredients without it will be approved by the Ministry of Health, Labour and Welfare (MHLW). Many procedures for regulatory acceptance still require animal testing, and i [....] » Read More
Intrinsic skin aging occurs with time chronologically. Cumulative external factors (depicted as the “Exposome”) contribute to skin aging by accelerating the change of texture leading to a decrease in elasticity and the development of the typical leathery appearance sh [....] » Read More
Eyebrow contour provides facial expression and is significantly important to a person’s appearance, contributing to the femininity or masculinity of the face. Without them, a person feels incomplete, self-conscious, and unnatural and this can cause great distress and anxiet [....] » Read More
Asian eyelids have several characteristics that distinguish them from the eyelids of people from European and African descent. These include 1) low, poorly defined or absent lid creases, 2) pronounced fullness to the upper and lower lids, 3) narrow palpebral fissures and 4) epica [....] » Read More
Topical use is the main advantage for dermatological therapy due to the outer-layer features of skin. Consequently numerous preparations are available for the dermatosis. However, the efficacy evaluation of different preparations accurately is always very difficult. The tradition [....] » Read More
The use of a daily skincare regimen, that delivers dermatologic benefit, has a greater impact on how a person’s skin feels, looks and behaves on a daily basis than any other aspect of what a person might do to their skin. The combination of OTC and novel cosmetic ingredient [....] » Read More
Over 200 single nucleotide polymorphisms (SNPs) have been found to be associated with food allergy (FA) in genome-wide association studies (GWAS). A Genetic risk score (GRS), is an index that can be derived from genome-wide association studies to summarize the genetic risk encomp [....] » Read More
Involving using of human stem cells in Androgentic Alopecia that holds a great promise. There are numerous sources of autologous human stem cells being used for the treatment for AGA. A recent new discovery source of autologous human stem cells is harvested from human hair follic [....] » Read More
Morbihan disease is a rare condition, manifested centrofacial, solid, permanent edema, accompanied by multiple telangiectasias, papules-pustular elements, with a primary lesion of the middle 1/3 of the face. Typical is a dark red edema with a purple tint, turning into induration. [....] » Read More
Concerning the charms of beautiful cheeks of womens are no need to be mentioned. Many surgical approaches can be done successfully, but frequent unnatural looking wind blowned surgeried faces are encountered. Specifically for many faced asin ladies. My Challenges for rejuvenation [....] » Read More
Aging of the skin is an actual problem of modern dermatology and cosmetology. Currently, it is widely accepted to consider such types of skin aging as natural, postmenopausal and photoaging separately from each other. While natural aging of the skin is a genetically programmed pr [....] » Read More
Introduction: Dermal Pigmentation of face and neck is a common refractory condition of varied etiology with minimal effective remedial modalities available. Inspired by the study of combined IPL plus 1064nm QS- ND: Yag treatment for melasma by Cunha et al from Brazil, where they [....] » Read More
Importance: Clinical symptom is often a direct method to evaluate the treatment effects. With the emergence of new EGFR-targeted drugs in market and its wide utilization, this study aimed to determine whether adverse skin event as a survival indicator for patients treated with EG [....] » Read More
Pranoprofen (PF), 2-(5H-[1] benzopyrano- [2, 3-b]-pyridin-7-yl) propionic acid, is a nonsteroidal anti-inflammatory drug used in ophthalmology. Recently, some articles have reported the effect of this drug for the treatment of skin diseases. Nanostructured Lipid Carriers (NLC) ar [....] » Read More
Introduction – ds-DNA-IgG and ss-DNA-IgG are antinuclear antibodies (ANA) designed to determine autoimmune antibodies of class G (IgG) to double-stranded (undenatured) DNA (ds-DNA) and single-stranded (denatured) DNA (ss-DNA) in human serum. The aim of the study was to dete [....] » Read More
Facial puffiness commonly experienced by women may not pose a health risk but it can be a cause of cosmetic concern. The objectives of this study were to determine whether self-perceived facial puffiness can be measured objectively, and also to understand how it is affected by ag [....] » Read More
Introduction: A wide range of behavioral processes and physiological functions in the body are varying in a highly controlled and periodic manner in function of day time. This oscillatory system, called circadian rhythms is highly synchronized and allows organisms to adapt to the [....] » Read More
Title : Role of the transcription factor p63 in regenerative capacity of skin stem cells
Makoto S, Boston University School of Dental Medicine, United States
Homeostasis and regeneration of the skin are maintained by selfrenewal, proliferation, and differentiation of tissue-specific stem cells. We have shown previously that the transcription factor p63 plays an essential intrinsic role in regulating self-renewal of skin stem cells. In [....] » Read More
Title : Aesthetic Blepharoplasty without skin Resection
Ricardo Hoogstra, University of Buenos Aires (UBA), Argentina
Aesthetic Blepharoplasty is one of the most frequent procedures. Despite of his simplicity., complications are very frequents also in the hands of very expertise plastic surgeons. The most frequent side effect of upper blepharoplasty is the descend of the eyebrow.,which give to t [....] » Read More
Title : Prevention of skin aging and skin cancer by sunscreens: UV or light protection
Jurgen Lademann, Charite - University Medicine Berlin, Germany
Skin aging is determined not only by genetic aspects but mainly by environmental factors and the lifestyle of each individual. Solar UV-radiation, nicotine and alcohol consumption can cause free radical formation in human skin. In small concentrations free radicals are important [....] » Read More
Title : Uncoupling oncogenic and tumor-suppressive activin functions in melanoma
Daniel B Constam, Ecole Polytechnique Fédérale Lausanne, Switzerland
Melanoma and squamous cell carcinoma and many other cancerous cells frequently secrete Activin-A, a TGFβrelated factor that normally regulates wound healing and the menstrual cycle. Activin-A accumulation in plasma associates with poor prognosis e.g. in lung adenocarcinoma a [....] » Read More
Title : New perspective combining peeling mesotherapy mesobotox and microinsulated radiofrequency as combo treatment for acne
Anggi Y Utami, Indonesian Medical Aesthetic institution, Indonesia
Acne is a common inflammatory skin disease that affects pilosebaceous skin units. This usually long-standing disease can have severe psychological effects and can leave patients with severe skin scarring. There are a number of pathophysiologists who are recognized to be responsib [....] » Read More
Title : Science-based skin care to prevent aging and pigmentation with special reference to Japanese skin
Desmond Fernandes, University of Cape Town, Saudi Arabia
Without doubt, by understanding the molecular changes in skin that cause photoaging and the processes that induce intrinsic ageing, we can then devise a scientific strategy of treatment. Foremost amongst the molecular changes is the destruction of vitamin A, which is naturally fo [....] » Read More
Title : Effects of lipopolysaccharide on the maintenance of skin homeostasis and improvement of skin problems including atopic dermatitis
Chie Kohchi, Macrophi Inc, Japan
The skin is directly exposed to the environment, and its homeostasis seems to be maintained by a crosstalk between the skin resident bacteria and environmental bacteria. Kasahara et al. reported that many bacteria that are found in forests and farms live on the skin of people wit [....] » Read More
Title : Morphometric study of facial wrinkles and aesthetic skin as derma roller treatment combined with Platelet Rich Plasma (PRP)
Oyunsaikhan Surmaajav, Anagaakh Urlag LLC, Mongolia
Background: Facial wrinkles are a multifactorial, complex process that negatively affects individuals’ appearance, consequently their quality of life. The treatment for these wrinkles varies with the degree of severity. This prospective study aimed to evaluate the clinical [....] » Read More
Title : Rejuvenation by New Thread Lifting (SLONA lifting) and Filler(S signature filler)
Wonseok Choi, V Plastic and Aesthetic Clinic, Korea, Republic of
Minimal invasive surgery is currently the most popular field in the field of cosmetic surgery. Especially, Botulinum toxin, Filler, and Thread treatment is the most commonly performed minimal invasive procedures. One of the key treatments is Filler and Thread. Filler must hav [....] » Read More
Title : Efficacy of kinesio taping in the early postoperative period
Hyung Woo Yim, Forever Plastic Surgery Clinic, Korea, Republic of
Kinesio taping (KT) is used worldwide to prevent and treat musculoskeletal injuries. This study is to investigate whether the application of KT prevents or decreases bruises, swelling, and pain after surgery, thus improves patients’ postoperative morbidity. Materials and [....] » Read More
Title : New mini invasive technique of rejuvenation and adelagazamiento (visual) of the lower third facial and top cervical third
Gerardo Rafael Manuell Lee, Hospital Sedna, Mexico
Methods :Traction of the auriculo-platysmal fascia is performed, through the rotation and traction of the auricular pavilion and the facial SMAS, with minimal incisions and fixation to the deep fascia and periosteum, this technique has been carried out in two modalities: the firs [....] » Read More
Title : Treatment of vitiligo patients with high doses of oral vitamin D3 combined with melanocyte stimulation and pigment cell transplantation is safe and efficacious
Ulrich AMON, International Center for Skin Diseases DermAllegra, Germany
Vitiligo is a complex autoimmune skin disease resulting in varying patterns and degrees of depigmentation. The genetic and etiologic background are thought to be multifactorial. As in other autoimmune diseases regulation of immune dysfunctions through vitamin D seems to be import [....] » Read More
Title : Successful use of grenz rays for disseminated superficial actinic porokeratosis
Laurence Imhof, Department of Dermatology, University Hospital Zurich, Zurich, Switzerland
Disseminated superficial actinic porokeratosis (DSAP) is a rare keratinization disorder with potential malignant transformation, for which present treatment strategies show limited success. In a retrospective study the response of DSAP lesions to grenz ray radiotherapy (RTx) was [....] » Read More
Title : Efficacy of biophysical energies on healing of diabetic wounds
Rachel Lai Chu KWAN, Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong
Chronic wound is a common complication seen in people with diabetes, and is the leading cause of nontraumatic lower limb amputation. Diabetic polyneuropathy and microangiopathy that happens in people with diabetics may impair the wound healing process, thus the wound can get stuc [....] » Read More
Title : E-BABE- complications, unfavorable results and critical analysis of the double eyelid procedure
Adolfo Napolez, Southern Illinois University School of Medicine, United States
The Double Eyelid Procedure is one that is potentially fraught with unfavorable results as well as numerous complications due to the fact it is a procedure based predominantly on symmetry, precision and tissue characteristics with errors measured in millimeters. Coupled with sign [....] » Read More
Title : True causation of intractable atopic dermatitis and actually effective treatment by mite fauna investigation of patients’ homes followed by environmental improvement
Hideo Nakayama, Meguro Chen Dermatology Clinic, Japan
There is enough accumulated evidence to conclude that house dust mites (HDM) are the most significant causes of atopic dermatitis (AD). HDMs are known to increase serum IgE and RAST scores for Dps and Dfs, and will often show positive results among AD patients when a patch test u [....] » Read More