Title : Relationship of periorbital melanosis with pigmentary demarcation line-F
Introduction: Periorbital melanosis (POM), darkening of skin around eyes, dark circles is a common cosmetic concern and is an ill-defined entity to-date. Pigmentary demarcation line (PDL-F) is physiological abrupt transition line between hyperpigmented skin and lighter areas [2,3].
Objective of the study: To explore the relationship of POM and PDL-F by clinical and histopathological parameters.Patients and Methods:50 consecutive patients of POM attending the outdoor clinic of Dermatology Department of DHQ Hospital,FMU, Faisalabad from 15•h July to 15'" December 2022 were enrolled in this study with their consent. History of onset, affected family members, and triggering factors were noted. Photographs were taken from front and side views with their eyes open and closed to see extent and relation of POM and PDL-F. Depth of pigmentation was determined by Wood's lamp examination.2-mm punch biopsies of POM and PDL F of the same side were carried out in 5 patients. Inclusion Criteria: Patients of any age and either sex. Clinical diagnosis of POM.
Exclusion Criteria: Patients having melasma, lichen planus pigmentosus, Drug induced pigmentation and Post inflammatory hyperpigmentation. Wood's lamp examination: Diminished intensity or imperceptible pigmentation of both POM and PDL-F.
Histological examination: Variable degree of melanin pigment within dermal macrophages Conclusions: POM and PDL-F is a common, chronic and same pigmentary problem. POM is an extension of PDL-F, not two entities, but one. It is a Dermal nature of their pigment.This fact correlates with theineffectiveness of the various therapies in POM and PDL-F.
Keywords: Facial hyperpigmentation, Periorbital melanosis, Pigmentary demarcation line-F